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Immediately is available ACOMPLIA in Germany and beyond that also in Great Britain, Denmark, Ireland, Finland and Norway one offers. The medicine is available for using up as 20-mg tablet, which is taken once on the day before the breakfast. On 21 June 2006 the European commission had given the permission for ACOMPLIA (Rimonabant 20 mg/day) for all 25 member states of the European Union for the following indication:
Additionally to Diät and movement on the treatment of adiposity (BMI> 30 kg/m2) or over-weighty patients (BMI> 27 kg/m2), which exhibits one or more factors of
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Acomplia
risk beyond that such as Typ-2-Diabetes or Dyslipidämie. ACOMPLIA sanofi aventis one discovered and one developed. It is a first representative of a new class of medicines, the so-called CB1-Antagonisten. Into ACOMPLIA contained active substance the Rimonabant blocks selectively the CB1-Rezeptoren at multiple effect places such as muscles, fatty tissue, liver, stomach, intestine and brain. Accomplia the overactivity of the EC-system restrains and causes in this way a reduction of kardiometabolischer factors of risk like degraded HDL, increased triglycerides, increased HbA1c and increased waist extent:
Over-weighty patients can reduce their body weight clearly by regular income of the new active substance Rimonabant and lower thus their metabolic risk clearly regarding a diabetes or a heart cycle illness. If the effect of the weight reduction could be documented so far only over maximally twelve months, now results of a new study occupy that the reached weight acceptance with Rimonabant can remain also long-term.
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