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ACOMPLIA of sanofi aventis one discovered and one developed. It is a first representative of a new class of medicines, the so-called CB1-Antagonisten. Into ACOMPLIA contained active substance the Rimonabant blocks selectively the CB1-Rezeptoren at multiple effect places such as muscles, fatty tissue, liver, stomach, intestine and brain. ACOMPLIA the overactivity of the EC-system restrains and causes in this way a reduction of kardiometabolischer factors of risk like degraded HDL, increased triglycerides, increased HbA1c and increased waist extent:

Over-weighty patients can reduce their body weight clearly by regular income of the new active substance Rimonabant and lower thus their metabolic risk clearly regarding a diabetes or a heart cycle illness. If the effect of the weight reduction could be documented so far only over maximally twelve months, now results of a new study occupy that the reached weight acceptance with Rimonabant can remain also long-term.

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